Main Subject - Finance

Most of the people in the United States and Japan nowadays count almost exclusively on their credit cards in order to maintain the lifestyle they

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

are used to. There are literally millions around the world who plan their monthly spending or budgets in general along the line of credit their

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

banks give them. That may be as it is, but it turned into an absurd situation for most of them. Before there was such a thing as credit cards p

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ople lived from paycheck to paycheck. So by the end of the month they had spent all the money they had earned, waiting for the next payslip. Bu

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

they had spent THEIR money.

Nowadays people still live from paycheck to paycheck, but now they need all the salary or wage they get to pay off

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

heir credit card. So at the beginning of the month they are already broke and have to do the rest of the month's spending on credit cards, which

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

in turn they have to pay off at the beginning of the next month. It's a vicious cycle and a multi - billion dollar business for the banks. Peop

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

le will always spend more than what they have or will be able to pay off the following month and therefore have to pay obscenely high interest on

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

their cards.

Another negative side effect is that people have such a high credit debt that they are unable to save some money for a new car, for

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

example, or a new house. They are condemned for practically the rest of their lives to go through this repeated cycle.

Now, there are countries

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

like Germany, for example, where credit cards are highly unpopular. The Germans use them, yes, but very expeditiously. Germany and others of h

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

r European neighbors have a very developed financial culture where spending money which you don't have is frowned upon. It's the diaspora for Am

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rican Express, Master Card and others. That?s why they love to do business in the United States, because there it's socially accepted that you s

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

end money first and than work for it.

The Germans, to stick with this example, are famous for their internal savings. The country as a whole mi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ght be indebted, like any other nation on this earth. But Germany's debt is always set off by the private savings of its people. Every househol

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

has on average about $1,000 in a savings account which is never spend. It's for the famous emergencies, few of which actually happen. But add

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

p a thousand dollars for each household and you'll find that the countries balance sheet is in the blacks.

Back to the States. Most young peopl

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

are told to establish, early on, their credit line and it does look to them like free money. Until, that is, they start to realize that they ha

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e to pay off at some point or other these ridiculously high credits, or else. So a lot of people resort to the old trick of paying off one credi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

card with another, spending their lives juggling about their different credit cards. They end up with multiple banks they owe to instead of one

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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