Main Subject - Business

Fired, canned, laid off, let go. Whatever you want to call it, it could happen. Sometimes, people see it coming. Other times, they're caught completely

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

off guard. Either way, the process of surviving the loss of a job is the same, and it takes hard work and resolve to do so.

Let go

For most people,

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

heir initial reaction to a job loss is shock, followed by anger and feelings of victimization. While these reactions are completely normal, dwelling on

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

them is a mistake. As the old adage goes, you need to pull yourself up by the bootstraps and move forward. Feel sad, get mad…and move on! The worst th

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ng you can do is bring a toxic attitude with you wherever you go, or wallow in self-pity.

Examine the evidence

If you've been fired, you need to asse

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ss why. In some cases, it has nothing to do with you, but if it does, you owe it to yourself to examine the reasons. If your behavior, attitude, perfor

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ance, or abilities were to blame, ask yourself how you can learn from the experience so you don't repeat the same mistakes. Being fired can sometimes p

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rovide a big wake-up call that spurs people to positive change and a brighter future.

Don't blame the messenger

A layoff is usually an entirely diffe

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ent situation than a firing. Most of the time, layoffs are about company decisions to restructure, downsize, or cut perceived fluff. Rarely are they ab

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

out individuals, no matter how personal it may feel. In most cases, companies realize it's a decision that affects people and they don't usually make l

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

yoff decisions quickly or easily. Whether or not you're given notice and a severance package is based on the company's ability to do so, not whether or

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

not they care about you. Still, knowing that a layoff isn't about you isn't much help when you're left jobless and unsure where you'll be tomorrow. How

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ever, it's absolutely imperative that you do not take the situation personally and allow it to turn you into an angry and bitter person.

Misery loves

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

iserable company

Yes, you need to grieve, get angry, and vent to the appropriate people. What you don't need to do is dwell on it and bicker to others

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

for days on end. It might feel good to talk bad about your employer, but while doing it, you're dragging yourself down as well as everyone around you

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

and you're obviously not out looking for a job!).

There is a time and place for negative rhetoric, but those places don't include your current job (if

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

you're still there), a job interview, or at home every night. You can damage job prospects by bad-mouthing a former employer, and you can isolate your

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

elf and loved ones by remaining caustic and withdrawn.

Process, positive thinking, and productivity

Try writing your thoughts down, limiting the amou

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nt of time you allow yourself to be angry, finding positive people to pull you up, and keeping yourself busy with both job-related and non job-related

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ctivities. By limiting negativity and focusing on positive and productive thinking, you'll be out of the dumps and on your way to a new job much faster

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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