Main Subject - Internet and Businesses Online

We have entered a new era in airline booking with the creation of YACA (yet another cheap airline): Skybus, operating out of all places, Columbus Ohio. I mean no disrespect for the town, where parts o

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

f both sides of my family once lived before they all retired to Florida or Vegas. And I wish this new entry well, even though they don’t fly anywhere near where I live.

There are several things that

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

are interesting about Skybus. First, their Web site is modeled after EasyJet and Jet Blue and has a nice booking engine where you can quickly figure out what flights are available at what prices. I ca

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ll this Strom’s first law of airline booking: a customer wants the utmost in transparency and ease of use when it comes to finding the cheapest fare. The sites and airlines that do this well will succ

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ed. It isn’t enough to know that I can find the cheapest seat, but that I can have some reasonable assurance that the seat I buy today will continue to be a good deal next week too.

I like the calend

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ar view that Skybus and EasyJet use, but I also like how Southwest shows you the prices of flights the day before and after your initial query. If you have some flexibility in your trip, it is very ea

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

sy to use.

Other travel booking sites have gotten into doing some interesting things with searching the airline reservation system, and the one that I have come back to more than once is Kayak.com. I

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

t takes some learning to figure out how to eliminate and focus on the flights that you want to take, and I am not sure of its entire universe of fares, but for trips where you have to connect and coul

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

use a variety of hub cities, it has a lot of promise.

My second point about Skybus is you can’t call them – operators are definitely NOT standing by to take your reservation, they are 100% Web-only.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

If you have a problem, send them an email. I think this is great until you have a problem and need someone to resolve it. And time will tell if they are responsive via emails.

We all have our horror

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

stories about airline travel, especially after this winter, and I will share one of mine here with flying United. One of the things I learned about United is that their call center is really sub-par.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Clearly, they have outsourced this offshore, and the level of expertise is definitely lower than what I have seen on other airlines. About a month ago, I ended up sitting on the tarmac here in St. Lo

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

is, knowing that I will miss my connecting flight in Chicago. So I get on the phone and see if I can at least expect that a seat for the next flight out of Chicago. The call center people – and I trie

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

d multiple times – all were spectacularly unhelpful, even going so far as to say that the connecting flight was sold out. Of course, when I got to O’Hare and got on the next flight it was nearly empty

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

, and I had no problem finding a seat.

But I will never fly United again, if I have a choice. Now trying to project that experience with Skybus, they still need something for passengers who get delay

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ed. Perhaps at the Columbus hub they will have plenty of terminals that you can access – I haven’t been there so can’t say – but what if you have problems at their remote airports where the Internet c

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

nnectivity isn’t that good, and there is only a single flight per day?

My third point is that Skybus is also being transparent about charging for things beyond the space your body fills on their plan

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

es. Want early boarding so you can get the seat of your choice (they don’t assign seats, ala Southwest)? Want to check a bag? Change your ticket? They are upfront about these charges, although they co

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

uld do a better job of enumerating them in a single place on their site. They are also upfront about those oversize passengers that should book two seats, but usually don’t. Having sat next to quite a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

few of these people who “compromise any portion of the seat next to them” (a wonderful locution from their site), I applaud this wholeheartedly. One nit: golf clubs aren’t charged extra but bikes are

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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