Main Subject - Internet and Businesses Online

Brief History

JavaScript first emerged in 1996 and was a programming language written by Brendan Eich for Netscap

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e. Initially, it was developed so the code could be embedded in Web pages so it could process numbers and modify t

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e contents of forms. Over the years, the use of JavaScript code has increased exponentially and is now used in a g

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

eat many ways, including image manipulation and mouse-over effects etc. Although it is now such a popular programm

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ng language in it’s own right, there are few minor niggles and issues to be aware of.

Advantages

Speed - because

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

all the code resides on what is known as the ‘client-side’, response times are fast. The alternative to client-si

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

e is known as ‘server-side’ and this involves your computer having to wait for a response from a command or instru

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

tion to a computer server somewhere out on the Web.

Simplicity - JavaScript as a computer language is not too dif

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

icult to learn and there are stacks of resources available on the Internet to help you. It is also possible to do

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

wnload masses of high quality code example free-of-charge and this can help you to reduce time demands and also to

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

assist you in understanding the language dynamics.

Versatility – Unlike PHP and SSI scripts for example, JavaScri

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

t is highly co-operative with other computer languages and can be used in conjunction with a great many applicatio

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

s. Another good thing about JavaScript is that it can be inserted in any web page irrespective of your chosen exte

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nsion (e.g .htm, .html & .php etc.).

Load on servers - Because it is client-side, there is no demand placed on th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

server where the website resides.

Disadvantages

Security - An important consideration is that because the JavaS

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ript code is executed on the user's computer, there is a chance of it being exploited in a malicious way. For this

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

reason, some people cautiously disable JavaScript from operating on their computer. This is not the major consider

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ation, but it is worth bearing in mind as you develop Web applications.

Browser incompatibility - An ongoing prob

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

em is that JavaScript can be interpreted in different ways by the various browsers. The most important thing is th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

t you verify the operation of your JavaScript code in the major browsers and do not get too hung up about the rest

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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