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Free tools for video manipulation and editing in Linux aren’t that hard to find if you kn

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ow where to look.

Here are my favorites:

Avidemux is a free video editor designed for s

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

mple cutting, filtering and encoding tasks. It supports many file types, including AVI, D

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

D compatible MPEG files, MP4 and ASF, using a variety of codecs. Interestingly, it’s avai

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

able for Linux, BSD, Mac OS X and Windows under the GNU GPL license. I haven’t tested Mac

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

OS X and Windows versions, but the program runs fine under Ubuntu Linux (Dapper Drake).

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ttp://fixounet.free.fr/avidemux/

For file conversion, there’s FFMPEG, which is free--but

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

you’ll have to learn to use it through the command line. Unfortunately, the MAN page for

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

the program isn’t very clear.

To save some of you the trouble of figuring it out, here’s

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

a quick tutorial.

Let’s say you want to convert a file called MYVIDEO.AVI to the mpg for

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

at, which is the format supported by the K3 CD burning program. After installing FFMPEG (

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ou can use Synaptic Package Manager), fire up Terminal.

From the command line, navigate

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

o the folder where the file is kept. So you might type:

cd /home/user/Converts

to go to

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

the folder where the file is kept.

Then type the following at the command line:

ffmpeg

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

-i MYVIDEO.avi -target ntsc-vcd MYVIDEO.mpg

and hit Enter. That should get the conversio

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

program started, and you ought to see some text scroll by in the Terminal window. Don’t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ccidentally close the window, because that will stop the conversion. You can minimize it,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

however.

To convert an avi file to SVCD format, you would type:

ffmpeg -i MYVIDEO.avi -

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

arget ntsc-vcd MYVIDEO.mpg

There’s a GUI front-end for FFMPEG on Mac OS X, but I haven’t

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

found one for Linux.

For ripping DVDs, I use AcidRip. Very simple but fast and efficient

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Establishing and managing office space can be a real headache – which is why more and more businesses of all sizes and types are choosing serviced or managed office solutions.

You've created a great site with lots of great content and you have chosen your web host. So- big question- what's next? Unless you are especially altruistic (and if you search the web, you'll be surprised to see just how many people are), you'll probably want to make some money out of your efforts. But how do you turn this stream of dots on a screen into a revenue stream? Here are a few pragmatic tips that might help… basic steps that will get you started and (hopefully) start you thinking.

You’ve just come across a fantastic product and you’re thinking of signing up as Affiliate but before you get carried away, here are a few pointers that can save you both time and money!

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