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Dealing with difficult people at the workplace is an interesting study.It is human nature to observe people that you have to work w

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ith. We have all done that. Everyone has good and bad days, no matter how dedicated to a job you are. However, there are those peop

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e that just stand out in a given day. You know who they are. They come in different varieties.It all starts at the time clock, befo

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e your shift begins. There they stand, grumbling about one thing or another and threaten to leave. You only hope that they do, but

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

hey don't.After getting a cup of coffee you say your good morning. Some just meekly smile, others just totally ignore you. I often

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

find myself just standing there, but nothing happens. All I hear are the meaningless complaints about their day or shift.Then there

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

is the other one. I call her chatty Kathy. She never shuts up. She constantly talks, just to have something to say. She's good at t

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

is, but never knows how to listen.

She actually got off the wrong floor babbling away, and I let her do it. Served her right!Oh, a

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

d then there's the clique. You know about that, I am sure. You want to be a part of the circle, but you just don't fit in. You can'

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t get a decent word in because they don't want to hear that you won $45.50 on a scratch off lottery ticket. Silly me, thinking that

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

was exciting!During break, I find myself sitting by the quiet one. Not a word spoken. I can see this person from the corner of my e

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e, and ask myself, "Is stress doing this to this poor human being?" "Aren't these poor souls aware of how they are behaving?", I as

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

myself. If I sat on that bench, knowing another person is sitting there too, I would experience apnea and would have to breath and

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

start talking, otherwise I would choke!

I wish that people would feel more secure and personable. Isn't that what our parent rais

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

d us to do? Apparently, not everyone acquired this heart-felt skill. Their behaviors have been difficult for so long, they often ha

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

e no clue how they are affecting others on the job.I do have that rare person at the workplace. We can talk about anything. When we

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

arrive at work, we smile and give each other a hug, knowing that we have each other to talk to.

No matter how difficult the day go

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

es, I can depend on her to give me an encouraging word, and that bond gets me through my day.Finally, it's time to punch out. While

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

I'm standing there, I overhear a dissatisfied employee saying to another, "you can quit this place." "Why quit," says the other. "B

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

cause , I'm not the difficult person here." "All I'm trying to do is do my job."I punch the clock and leave with a smile on my face

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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