Main Subject - Internet and Businesses Online

To clarify, I am not talking about rotten eggs or that horrible stuff the poor depression dwellers had to eat, I am talking about computer e-mail spam.

What is this spam I speak of?

Spam is best define

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

d as unsolicited and unwanted commercial electronic messages or e-mails that are sent to large numbers of people.

Ask any computer user and the most annoying thing about having and using e-mail is the a

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

nnoying amount of spam you get. It is predicted that spam could eventually kill the usability of e-mail unless effective barriers and law changes are introduced. In 2003 it was reported that 40% of all e

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

-mail traffic in the US was spam up from just 8% in 2001. Over the past 6 months this figure has doubled. Hotmail a popular e-mail service, says that 80% of e-mail coming to their servers is spam.

You m

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ght say that I don't get as much spam as I used to. Well this is thanks to internet providers and businesses filtering this out before you see it. One problem with spam filters is that occasionally users

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

encounter false positives in which important and legitimate e-mail gets blocked. Due to these necessary anti-spam measures, the costs involved are huge. Not only does all this excessive internet traffic

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

clog up the internet freeway, but all these e-mails are downloaded to servers before the anti-spam software deletes it. Businesses worldwide report that 20% of all e-mail received is spam. It is estimat

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d that the true cost of spam for businesses in the United States alone is $8-9 billion US dollars per year.

Why is there so much spam?

The simple answer is that there is a market for spam. If people di

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

dn't buy from spam e-mail there wouldnt be any spam. All the spammer needs is for one person, out of a few hundred thousand e-mails, to buy something and it makes the whole process worth while. Sending t

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

he spam requires little effort on the spammers part as the computer automates the process meaning that it is very easy to send out over a million e-mails an hour.

What is the world and in particular New

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Zealand doing about all this spam?

On the 23rd of February '05 the Information Technology minister, Paul Swann, released a proposed law will that make it illegal to send spam that originates from NZ. On

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ly problem is that only 1% of spam originates from Australia and NZ, and to actually catch and prosecute a spammer is very difficult due to spammers being good at hiding there identity.

In April '05, a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

30 year old spammer in the United States became the first person to be prosecuted for spamming. He was sentenced to a nine year prison term. He is described as a modern day snake oil salesman being the e

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ighth most prolific spammer in the world, sending up to 10 million e-mails a day from his house. His income was $750,000 US per month, with one in every 30,000 e-mails sent generating money. He sent out

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

o much e-mail that he received, on average, 15,000 credit card orders a month, each order worth an average of $US40. His total worth is $24 million US dollars, he advertised pornography, fake products an

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

d services. During the court case the assistant attorney general said and I quote "When your marketing to the world, there are enough idiots out there who will be suckered in."

Remember that spam is onl

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

y a problem due to people purchasing from spam e-mail, if there was no demand there would be no spam, security firm Mirapoint, reports that 1 in 10 people buy something from spam e-mail.

So how do I pro

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ect myself from spam?

There are a three main ways to stop being spammed.

The first and the best form of defence is not to give out your personal e-mail address. Don't publicise your address in chat roo

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ms or fill in forms on a website. For this purpose, you are best to use a public e-mail address such as a hotmail account, as some web site owners are more than happy to sell your e-mail address to a spa

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

mmer.

Secondly use an internet provider that controls and monitors spam.

Thirdly install anti-spam software on your PC.

Therefore in this day and age there really is no need to eat green eggs and spam

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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