Main Subject - Internet and Businesses Online

Everyone who uses the internet has more than likely been targets of spam at one time or another. At first they are easy to dismiss for internet experienced persons, however for the inexperie

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nced user of the internet, the messages contained can sometimes be intimidating and in some instances lead to trouble (I will come onto a personal example later).

Spam can take several forms

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

; email and search engine spam are just two, but the one we will concentrate on in this article, and also the one you will, and have most likely encountered, is via email.

Spam is defined as

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

unsolicited bulk mail, much of which is caught in your “bulk” or “trash” folder found in your email service provider control panel. You have probably often seen a mass of these types of ema

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ils in you bulk folders when checking for email that you actually have consented to receive, as many emails are caught by spam filters even though they should not. The majority of spam you m

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ay receive will be of a sexual or gambling nature, however over the past few months I have noticed an ever-increasing number of scam emails asking for sensitive information, claiming to be so

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

meone they are not.

Paypal and eBay scams are a prime example of these types of emails known as “phishing scam emails”. The email will be along the lines of:

“We have noticed an irregulari

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ty in your account details and require you to update them immediately. Failure to do so will result in the permanent closure of your account”

You can see how these emails can be pretty alar

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ming to an inexperienced internet user who may only occasionally use the internet to sell or buy items on eBay for example. Some of the emails will look very convincing, and will use the ima

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ges and symbols of the respective company, however be very cautious and take heed to the following important point:

If you are unsure of the legitimacy of the email, do not follow any link c

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ontained within the email to an external website. Instead, type the website address that you know is correct into your browser directly, so that you are safe in the knowledge that you are no

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

t using a fraudulent website.

Failure to do this may result in your account being hijacked by the scammer; it’s as easy as this. You follow the link in the email to a website claiming to be

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

, and also looking very much like one where you have an account. The website will ask you to input your username and password to access your account and voila, you will have now sent this in

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

formation to the scammer, allowing them access to your account containing sensitive information about you.

Another type of email scam that has been very popular is where you are notified to

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

be the very lucky winner of a lottery, even though you have never entered the lottery in the location claiming your success! This is where the example of a personal experience comes in. Man

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

y people reading this will be thinking “I’ll never fall for one of these scams”, however the unfortunate reality is that many people will do so. An elderly relative of mine received one of t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

hese lottery scams from Spain, and then insisted on following up with the email scam, even though they had never even entered the lottery draw. The only stumbling block was that the bank acc

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ount details required, needed to be sent by fax, which she couldn’t do, and despite the frustration that this caused I of course refused to help send it.

There are measures that you can take

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

to help avoid being targeted by spammers; a few have been mentioned here. However, in addition never reply to a scam email as it will notify them that the email address is live and also tha

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

t you have read the email, leading to further spam.

Of course there are many other threats from spam that are not discussed here, such as viruses and trojans being sent via email attachments

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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BB link (for phorums):
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