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We’ve all had this experience: You login to your email account, excited to read messages from friends, relatives, co-workers, or your girlfriend perhaps. You view the link to your inbox, and it says you have five mess

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ages. Fervently, you open your inbox, your heart is racing, you sit up in your chair a bit, leaning forward closer to the computer as you get ready to enter a new dimension.

What do you find when the page finishes loa

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ding? Well, you see a spectacular cornucopia of diverse, informative topics referenced in the “subject” for each email:

“Erectile Dysfunction? Look no further – Viagra, 90% off!”

“Get a 200 year mortgage!”

“Reverse

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

the aging process, regress back to infancy!”

“Make 10 million dollars per hour stuffing envelopes!”

These emails can try a man’s patience. It would be one thing if you had signed up for a service that emails to you,

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

every 5 minutes, titillating offers that, if they were true, could make you the richest man in the world with a mortgage that your ancestors, 200 years from now, will pay off in full, unless the house has completely ro

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

tted to the ground by then. However, most of these emails come unsolicited. How the heck did they get your email address in the first place? Well, I’m not really sure.

Just kidding! There are a variety of tactics t

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

hat spammers use to get your email address. Sometimes, you sign up for a service or buy a product from a website, and when you provide your email address during the order process, the individual who runs the website an

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d is collecting the information then turns around and adds all of those email addresses to his electronic address book and sends you offers from an email address associated with a totally different domain name so you do

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

n’t know it’s him.

Sometimes, these clever marketers skulk around message boards and other internet forums and just copy all of the email addresses for each of the people who have posted messages to the board, and they

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

can usually collect thousands of email addresses this way.

One way they can then build upon their treasure trove of stolen emails and grow their list exponentially is by then sending a joke to the various people on th

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

e list, something that they got off a website. The joke could be about George Bush. On the other hand, it could be a joke about someone who was born with a brain. When you decide to forward these witticisms to all of

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

your friends and list all of their email addresses in the “To” or “Cc” fields, you could be actually sending all of your friends’ email addresses to the spammer who sent you the joke. Clever spammers use programs that

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

grab email addresses when you forward or reply to such a message.

Sometimes these email larcenists send you an email message with an exciting subject that causes you to open it, and then there’s not much there, but by

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

opening the email you’ve unleashed a Trojan horse that crawls out of the email and onto your hard drive and grabs email addresses that are stored in folders on your computer where you save your “Buddy List” if you use

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

AOL, or strips the email addresses off of any and every email you have saved on your machine. The virus then proceeds to send all of these stolen email addresses back to the perpetrator, who may have just grabbed 100 e

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

mail addresses off of you, maybe more.

Finally, what happens a great deal of the time is people who are successful at building email lists, sometimes with a legitimate business where they have a huge database of 10 mil

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

lion or more email addresses, turn around and sell that same list over, and over, and over again to the spammers. This happens all of the time, and there’s really no way to stop it. Your email address has probably bee

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

n sold a thousand times since you started using email, you just don’t realize it.

So, how do you prevent spam? Well, you can use message filters that filter out emails that contain certain keywords (most email account

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

s come with a filter), you can block certain email addresses, or you can set up a very sophisticated set of “message rules” if you have email client software that has this option, and with this feature you can really se

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

t some very specific boundaries for your email account.

So, be aware of all these techniques that spammers employ, establish some ground rules for your email account, and you can probably avoid most spam in the future.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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