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Main Subject - Hobbit Spam - A Symptom Of A Future Problem
In early July of 2006 there was a prominent stream of spam messages that simply quoted three random lines of the
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
book 'the hobbit', with a subject header of 6 random letters. The popular belief is that this was a 'script ki
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
die' who had got hold of spam suite and was inept in it's use. This belief was reinforced shortly after when th
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
same messages began appearing with an image overlaid, a popular spammer trick(The seemingly innocent words allo
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
the message to bypass filters but all that is displayed on opening the message is the picture).
It's nice to p
It's nice to p
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
t seemingly random and pointless messages down to inept practice on the part of the spammer, but my personal bel
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
ef is this is not the case. To me this seems to look like a deliberate attempt to corrupt the improving Bayesia
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
Filter technology. Bayesian filters work by assigning a spam score to words that are found in spam e-mails. T
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
e more regularly they appear in a spam message, the higher the spam score and the more likely a message contiani
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
g those words is to be marked as spam.
Given that piece of knowledge, imagine the implications of a concerted c
Given that piece of knowledge, imagine the implications of a concerted c
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
mpaign of spammed messages that contains a short message of commonly used words. The 'spam score' of these word
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
is elevated, the effectiveness of the bayesian filter is diminished and when the real spam message is sent thro
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
gh the defenses are lowered, or indeed have been removed having provided too many false positives.
The obvious
The obvious
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
lue to me is in the way these messages are sent. Firstly the title is randomised. Many Bayesian filters treat
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
onsense as 'high spam' score. Furthermore title text is usually given a higher priority than body text. Thus a
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
nonsense title may be enough to get a message banned by itself, and combined with a common spammer trick such as
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
the picture overlay, it seems the spammer wanted these messages to be caught.
As more people come to rel
As more people come to rel
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
on Bayesian filtering, this will become a more and more serious problem. We already know spammers are prepared
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
to send out millions of messages just to get one sale. Now it appears that they are also prepared to make multi
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
le mailings to those millions of addresses just to soften up anti-spam defenses for their one commercial mailing
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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