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Main Subject - Spam - How Bad Is It
Spam is bad, we know this. It is a problem that doesn't seem to be getting any c
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
loser to going away. But the following numbers may be alarming to you, and demon
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
trate just how bad spam, the delivery of unwanted junk email, is becoming.
Ho
Ho
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
w Much Spam is out there?
In 1978 a single email was sent to 600 addresses,
In 1978 a single email was sent to 600 addresses,
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
he first documented example of spamming.
In 1994 the first concentrated spamming
In 1994 the first concentrated spamming
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
of usenet newsgroups reached an audience of several million.
By June of 2005 it
By June of 2005 it
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
was estimated 30 billion spam messages were sent every day.
In June of 2006 that
In June of 2006 that
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
estimate had risen to 50 billion messages per day.
By December of 2006 the esti
By December of 2006 the esti
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
ated spam messages sent per day had reached a staggering 85 billion.
This means
This means
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
in the past 18 months the number of spam messages being sent out has nearly tripl
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
d.
Where is it coming from?
Of the URL's in spam messages, 73.58% are lo
Where is it coming from?
Of the URL's in spam messages, 73.58% are lo
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
cated in China.
Other major destination URL's for spammer websites are located i
Other major destination URL's for spammer websites are located i
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
Russia, South Korea, Japan, Canada and the USA.
What is its Cost?
95% o
What is its Cost?
95% o
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
f viruses are spread by spam email in some capacity.
Spam messages cost US compa
Spam messages cost US compa
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
ies around $10 billion dollars during 2004 in lost man hours, software and hardwa
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
re requirements and consultation. The amount of yearly spam since this figure wa
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
estimated has quadrupled.
What does it get the spammer?
Jeremy Jaynes w
What does it get the spammer?
Jeremy Jaynes w
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
as charged with 3 spamming offenses in 2004. His reported income from spamming w
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
s $750,000 per month!
On the other hand, Vardan Kushmir, a known Russian Spammer
On the other hand, Vardan Kushmir, a known Russian Spammer
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
, was found dead in his apartment following several blunt force blows to the head
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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