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If you were suddenly made responsible for stopping spam on your Microsoft Windows network, what would you do first? Well, if you're like me, you'd probably Google "anti spam Excha

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nge server" or something similar to that.

Next, you'd spend some time reading a lot of reviews and articles about anti spam software suited for a Microsoft enterprise network.

L

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

astly you'd extract (from the articles) a list of the most commonly found bells and whistles that the current anti spam technology offers. You'd use this as a kind of wish list, o

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

r yardstick, against which you would judge all the possible anti spam solutions available to you.

Well, as you might imagine, I recently did that and here is a list of features t

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

hat any decent Exchange server-compatible anti spam solution should have. Your mileage may vary depending on what you need your solution to provide, but here's my list.

Filter sp

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

am on an Exchange mail server by doing one or more of the following:

Bayesian Analysis

Anti spam software of this sort allows you to begin by classifying one or emails

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

as "spam." Then, as your email arrives, the anti spam software looks at every other email to see if fits the definition you set. If it does, it goes to the spam folder; if it does

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

n't, it gets through to your inbox. But it doesn't stop there. Suppose an email gets through the "Bayesian filter." You can (and should) tag that email as spam -- so that the so

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ftware can add the characteristics of that email to its spam profile. What this means is that future emails of this sort will NOT sneak through.

In other words, the anti spam sof

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

tware that uses Bayesian analysis can learn and get better over time -- if you teach it to do so.

Downloadable spam signatures

Typical Bayesian analysis relies mostly on you

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

own unique description of what you consider to be spam -- and that's important.

But sometimes, two heads are better (and faster) than one. What if you could tap into a database

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

of spam characteristics that were put together by hundreds or thousands of other users? That what you get when you use anti spam software that periodically downloads new spam sign

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

atures. The big advantage is that you are casting a wider net. The disadvantage is that you might not agree with the crowd's opinion of what constitutes spam.

Keyword checkin

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

g

This anti spam feature identifies spam email by looking for certain words, like "Viagra." As you might imagine, this is a pretty crude method. For example, what if your name is

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Gay Smith? A keyword-checking spam filter might strike this email for containing objectionable content. Don't laugh -- I just read about this very thing happening.

Header ch

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ecking

This is a pretty basic form of spam blocking where the anti spam software checks to see if the email header shows tell-tale signs of spam:

Has the sender identif

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ied himself in the From: field? If not, it's probably spam.

Does the email have a "large number" of listed recipients (you can set the number)? If so, consider it the same as

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

spam.

Block email containing only remote images. To get around keyword or even Bayesian filters, spammers now send out email that shows only a picture, i.e., a graphic of

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

a bottle of viagra with an associated (non-text) caption. In addition, they might put a small amount of non-spam text in the message. Good anti spam software will block that. <

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

li>Check to see if the domain is real. The anti spam software will do a "DNS lookup." If the domain is not listed, the email is probably spam.

(End of part one of two

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Main Subject - 2000 Exchange Mail Server - How To Filter Spam (Part One of Two)

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