Main Subject - Internet and Businesses Online

A search engine's main job is to provide results which most satisfy a user's query. If they present a result that the user visits and doesn't agree that the document is about their query, there is a very good chance that the user may not use that search engine again. Most search engines pay no attention at all to the Meta description tags. Meta description and keyword

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

tags are hidden attributes that you can add to the front of your document which are supposed to annotate and describe the document. Since the users will never see this information, they will be disappointed if you stick in invalid keywords or fail to keep the description in line with the document's contents which usually is the case. Most Search Engine page ranking

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

algorithms rank pages based on the following aspects:

- Content of the website

- Representation of content, keywords, and links on websites

- Location and number of inward and outward links on websites

- Relevancy of search terms as compared to the websites

Given below is a brief description of the page ranking algorithms of some of the most popular search engine

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s. Google

You can submit your site to Google using http://www.google.com/addurl.html. Submitting your site will only make Google aware that your page exists; it is quite possible that your pages may get crawled even if you have not submitted. It is advisable to submit the home page and some inside pages. Inside pages are added to the submission, just in case the hom

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

page is found too slow to load or crawl. The pages that are submitted should link to the rest of the pages. Google indexes the full text that is visible on any page that it crawls. It generally does not index the metatags – keywords or descriptions.

When Google lists your page in the search results, the description that is displayed is the extract of text that is ar

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

und the first line where the search word appears on the page. It may thus be a good idea to write a good description of the page and build it around the most likely search term(s) and place that near the top of your page. You should remember that one sure way of getting your site listed and indexed is if there are several links that point to your site and such links a

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ppear on web pages that in turn have several other links pointing to them. The term ‘link popularity’ is used for this. It analyzes links of the pages that it has visited and this ‘link analysis’ helps to determine the ranking of the page.

Google uses a proprietary PageRank algorithm for determining relevance and ranking of pages in the search results. Location and f

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

equency of the search term on your web page are no doubt factors in ranking; however off the page factors such as link analysis are more important. Generally, Google provides search results based on relevancy, meaning that it returns a list of pages ranked by the number of other Web pages linking to each page, as well as other mathematical algorithms

Yahoo

Yahoo off

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

rs a human powered directory and visitors are offered the results from this directory. The directory is supplemented by web page index created by crawling. Yahoo currently uses Google for its crawler indexing. The directory is an important channel in the area of search engine marketing. It is popular and is used extensively by people to locate sources of information.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

Moreover the directory is a valuable boost to your site for crawling and ranking in other search engines, as the directory provides a high quality link to your web site.

When a visitor is looking for information or relevant sites, he/she could either browse through the hierarchy of directories and sub directories or search for an appropriate directory through a searc

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

interface. As your site can be listed in just one category, generally, the choice of category is an important step. Choose the top category that your target visitor who is making a search may select out of the different categories offered to him/her.

Select your target keywords and find out which categories relate to those keywords. For submission of non-commercia

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

sites also the Yahoo Express submission is recommended rather than the Standard submission option.

Listing of your site on the results page in your chosen category is in two possible sections (for most categories). One section is called Most Popular Sites and this is on top, while the remaining listing is Alphabetical in the second section on the page.

Yahoo does n

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ot reveal how it includes certain sites in the Most Popular Sites list. However link analysis, clickthroughs are likely to be factors. You cannot pay to be included in this section. Certain sites with sunglasses shown next to their name or @symbol shown at the end of the name reflect that Yahoo considers those sites as excellent.

Inktomi (MSN Search, AOL Search, Hotb

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t)

Inktomi is a search engine that does not offer its search services through its own site, but through Partner sites – prominent ones being MSN Search, AOL Search, HotBot and others.

Inktomi through its crawler creates three different indexes. Best of the Web index has around 110 million pages that it indexes on the web and considers high in link analysis. The next

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

set of around 390 million pages is indexed as Rest of the Web, considered as lower in link analysis. The third index is of paid inclusion. It also offers specialized regional indexes as well as targeted news, multimedia and directory indexes. It avoids duplication of the same page in more than one index. Link crawling and paid inclusion are the two most effective ways

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

to get covered by crawling. For bulk submissions to its paid program, it offers IndexConnect (for 1000 or more pages). Again there is a cost per click basis, with a monthly minimum.

Ranking at Inktomi is determined by a combination of factors including HTML links, keywords and description tags near the top of the page or in the Title tag. If the search string matche

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

with what is found at these places on the page, the ranking is higher. Link analysis and analysis of clickthroughs are other important criteria that it adopts.

AltaVista

AltaVista will accept free listings through its addurl link, but it also has paid inclusion features. Generally their crawler may visit every four weeks. Paid inclusion may be desirable if you have

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

a new website or pages or if your pages are refreshed every week or so and you do not wish to wait till the next cycle of crawling. There is an Express Paid inclusion service of self-service type for upto 500 pages at a time. This service will enable weekly crawling. Their bulk program called Trusted Feed will enable the pages to be directly linked to their index. Pri

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

cing for Trusted Feed is on a cost per click model with a monthly minimum. In this program you can submit the Meta data, descriptions and keywords directly to the index. Nevertheless, the engine will check whether the destination page has the same Meta data or not and could levy a penalty for spam.

AltaVista’s ranking policies are a combination of various factors. Th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

frequency and positioning of keywords and descriptions is important, so are Title tags or words that appear near the top of the page. Besides, it applies link analysis to determine relevancy and page ranking. It levies penalty on spamming and also it does not recognize invisible or tiny text, keyword stuffing, identical pages, mirror sites, and quick meta refresh tag

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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