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I remember when I first learned about Podcasting. It was via blog entries in Chris Pirillo's blog and Leo Laporte's blog. Both class act internet enthusiasts and both had a hand in making podcasting wha

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t it is today. However podcasting has become more of a business venture than the fun audio sharing that it was when it started out.

There are a handful of people that have alienated the idea of podcast

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ng. The idea that anyone can share audio not just the big time internet junkies. Take, for example, Kevin Rose, the one time tech television star that downgraded his career to online multimedia. He does

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

two podcasts, which there is nothing wrong with, but it's the way that he presents himself and hounds users to subscribe.

There is nothing wrong with promotion. If you are just starting out promotion

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s a great way to get the word out, and maybe become the next big thing. But then there are people and organizations that over promote. Over promoting is when you are already popular and have a good foll

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

owing and then you keep plugging away and hounding users to watch or listen even more. A perfect example of this is Kevin Rose. Of his two podcasts, both are in the top 15 (This week in Tech, 4, Diggnat

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

on, 12). That's great for him, but lets look at a post in his blog that was just a few days ago (while both were still in the top 15).

"Help out diggnation and subscribe today: If you use iTunes:

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

- Subscribe to the audio feed - Subscribe to the video feed Odeo: - Subscribe to the odeo audio feed iPodderX or other podcasting clients: - Raw RSS feed"

"Help out diggnation…". Help Out! He'

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

the number 12 podcast on iTunes and that's just not good enough. This is what I like to call greed. Greed to be better than everyone else, while not letting the little guy who's just starting out get s

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ome promotion.

If Kevin Rose wants to help out podcasting and not be a selfish person, he should probably promote on of his favorite podcasts, if he even ventures out of his own. Maybe he should get ou

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

there and listen to some more, some that aren't well know, that aren't in the top 15, that are maybe in the 100's. He may realize that there are some good podcasts that aren't overly popular. Then prom

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ote them on his site. He's got a good following he could get some people listening. Think of it as donating to the poor. You could just sit there in your mansion and suck up money while asking your maid

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

to get you more hot tea. Or you could donate some money and feel good about yourself.

If you were to look in the archives of Kevin Rose's Blog you'd realize that never once has he promoted someone else

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

's new feature or podcast, unless it was one of his "friends". All I hope is that someday Kevin Rose will realize that he's not the only human being on this planet; it wouldn't hurt the help the little

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

uy.

Some reading this article, may be wondering why I'm only focusing on Kevin Rose. The main reason is that he has a huge outlet of power, which he can thank TechTV for, and he uses it to only promote

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

himself. While on the other hand, Leo Laporte and Chris Pirillo tend to steer away from their online careers and give a little insight on their lives, and isn't that what blogging is for? While Leo and

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

Chris may not promote the small guy, you won't see them promoting themselves.

By just glancing at Leo and Chris's blog you can see very seldom self promotion. Now compare them side by side with Kevin R

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ose's blog. His is all self promotion, nothing looking into the life of Kevin Rose, nothing that helps the little guy, all self promotion so he can be number one at everything.

While I have the chance

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

'll finish off my rant on Kevin Rose by pointing on one simple thing. On the podcast "Diggnation", which I'm not subscribed to and dislike, they take the first three minutes to discuss beer. I hope they

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

realize that the majority, or if not the majority a large chunk, of their audience is under the legal drinking age. I do not believe that a podcast like this is the time or place for discussing alcohol

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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What if small business failures were very small instead of the five to one we now know they are? What if all small businesses paid back their small business loans? What if the local, county and state governments actually made it easier for small businesses instead of purporting that they were?

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