Main Subject - Business

Chicago – the city that has it all - from a diverse population, world-class educational institutions, and sensational restaurants to a breathtakin

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

g skyline and countless museums. Dubbed the ‘Windy City’ in 1893 by Charles Dana, the editor of the New York Sun – not for its weather but for its

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

long-winded politicians, Chicago has grown from a village of just 350 to a bustling city of almost three million.

Transportation
A

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

rports Serving Chicago
There are two airports that service the Chicago area – O’Hare International and Midway. O’Hare (ORD) is the larger

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

of the two airports, servicing over 70 million travelers per year. Located 20 miles from downtown, there are many transportation options including

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

public transport, taxis, shuttle services and hire cars.

O’Hare is an airport full of modern amenities and services. Recent upgrades have been co

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

pleted at the International Terminal 5 and additional renovations are underway at Terminals 2 and 3. Expected completion date is later this year.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Midway (MDW) is significantly smaller than O’Hare, serving 17 million travelers per year, but is only 10 miles from downtown. The Chicago Transit

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

uthority (CTA) offers transportation from Midway to downtown Chicago via the orange line buses. Other shuttles, regional buses and of course taxis

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

and car services also offer transportation to downtown.

Midway has all of the amenities that you would expect from a major airport, including res

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

aurants and gift shops. You can do some sight seeing in Concourse A where the Battle of Midway Memorial and an SBD Dauntless dive bomber are house

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

d.

Getting Around Chicago
Getting around town is much easier in Chicago than in some other big cities. Renting a car is a good option

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

if you need to visit different locations during your visit. The city has several major highways, but plan to avoid them from about 7 am to 9 am an

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

4 pm to 7 pm on weekdays – the traffic delays can be very frustrating. To avoid traffic delays, the train system in Chicago can get you almost an

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

where in the city – making it another good choice for business travelers that are sticking to downtown.

The Loop is the heart of the downtown bus

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ness district - named for the elevated train tracks that circle the area. All of the cities addresses begin at the corner of Sate and Madison stre

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ts in The Loop, making the streets easy to navigate. Each 400 increment in an address equals one half mile.

What to See
There is an e

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

dless list of things to see and do while in Chicago. If you like to shop, be sure to check out The Magnificent Mile, a one-mile stretch of shops b

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

tween the Chicago River and Oak Street Beach. There are also numerous internationally known museums in the city. The Field Museum of Natural Histo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

y is home to the most complete Tyrannosaurus rex fossil and the Art Institute of Chicago is famous for its collection of French Impressionists art

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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