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I will generally open the content email by telling them why I want t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

o share this, either because I get a lot of questions about it, or b

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ecause I have been thinking about it, or because it is something new

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

and I want to get them thinking. I will tell them that – why I am

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

riting about this.

Then I will shoot from the hip – tell people exa

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ctly what I am thinking.

I will also generally make the content ema

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

il action oriented. For example, if I write a content email about h

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ow to do something better, I will give them a set of action steps so

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

they can instantly apply my new insight into their business. I want

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

them to take action when they finish reading my email.

Speaking of

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

taking action, I want my readers to take some kind of action after

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

they read any email of mine. So in some sense, I want to train them

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

to take action. Sometimes that action will be to buy something. So

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

metimes that action will be to respond to me. Sometimes that action

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

will be doing something in their own business. But I don’t want th

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

e only time I ask them to do something to be when I am asking for th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ir money. I want them to take action on every email, so when I tell

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

them to take action by making a purchase, they will do it.

You can

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

train your readers, your subscribers, to buy from you – but first y

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ou have to train them to take action. So go ahead, take your action

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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