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In running an online think tank I have noticed that many people come and go who are only interested in attacking ideas or individuals i

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

n a combative way. This happens on Blogs, Internet Forums and many other online communication communities. Why does this happen?

Recen

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

tly in an online think tank such a combative chap came to criticize many ideas. One of the ideas was a stationary bicycle, which could

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

lso charge the spacecraft, ISS or Lunar Colony battery systems. He indicated that this was an ridiculous idea and stated;

“If this tru

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ly is a "think tank", then you must expect some reality to permeate it. Otherwise it's just a collection of delusions. Reality is reali

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

y, and all the happy thoughts in the world won't change it.”

Of course the idea originator had something to say about that comment ind

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

eed; First, I can back up every single one of my ideas, concepts and designs. Two, Your reality is not the reality, but rather a percep

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

tion based viewpoint you give out before considering all the possibilities. Three, there is also a created reality and reality is a mov

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ng target. Four, the naysayers said the same thing about the first propeller powered balloons. Five, the Wright Brothers were bicycle m

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

echanics so it is tradition.

So, all of your points have been defeated you have failed to shoot down this idea and wasted both our tim

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

s. That is not thinking. You have learned a valuable lesson, one I should not have to give to you considering your demeaning comment. Y

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ou are not owed an explanation when you attack with baseless arguments and are too self-ashamed to use your true identity. Not to menti

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

on you are annoying and what you are doing is actually illegal.

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

opic=1680">http://worldthinktank.net/wttbbs/index.php?showtopic=1680

So, use your real name and that might get us closer to a real

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ity of your intentions. The Electric Generation Stationary fold-up bike concept for Space Flight Stands; it is a good idea and I would

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ut one in my own spaceship, SpaceHab Capsule, Orbiting lab or small lunar or Mars colony, because it makes sense. Additionally I think

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

I’ll make one and put it in my motor home too.

Okay you want redemption? I tell you what post two original ideas in any category here

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

on this website. One to indicate you are actually a thinker and two as an apology for this comment: “Reality rears its ugly head again,

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

spewing red-hot truth to vaporize the delusions of fools.” For calling me a fool. Obviously I can take it and back up every word. But s

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ome folks might feel slighted by such comments and you would have hurt their motivation to participate. I speak for them. Think on this

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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