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    Many of the leaders in our society are guided by unhealthy intentions. Instead of seeking to serve the people and heal our nation’s ills, their actions and decisions are primarily motivated by their des
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    ire for power. Many of the people running our country are run by their addictions to approval, sex, power and control. Unfortunately, few truly healthy individuals want to submit themselves to the neces
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ary abuses inherent to our political races - the verbal abuse both given and received, the huge amounts of money spent, the integrity sacrificed through the concessions, lies and manipulations offered
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    in order to win.

    Our system of electing our officials is so corrupt that there is little possibility of attracting a person with a strong, personally responsible, loving inner adult self. This is not t
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    say that none of our elected representatives are honest and caring. Some are certainly motivated by positive intentions but, unfortunately, they constitute a minority.

    There is no training required in
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    personal responsibility to run for office. Our leaders are not required to heal their dysfunctional aspects in order to become honest and trustworthy people. The prerequisites for political positions
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ostly include having enough money, enough powerful people behind the scenes, being male, and being white.

    Our political arena is designed to attract wounded people who need approval and power in order to
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    feel worthy and validated. Obviously, such a person, with little or no internally derived sense of self-worth and integrity, is very susceptible to corruption. As the adage says: "Power corrupts and abs
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    lute power corrupts absolutely." Power corrupts when a person is motivated by his or her desire for power over others, and few people have accomplished enough inner healing to transcend the desire for
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    control over others.

    A healthy person in office who is more concerned with serving the people than with getting re-elected could accomplish a great deal. Such a person was depicted in the movie Dave. I
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    this film the actual president is in a coma and the White House officials, seeking to conceal the truth from the public so they can maintain control, put a look-alike into the president’s seat. Dave, h
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    owever, is a man of heart, and rather than allowing himself to be controlled he sets about making necessary changes - cutting money where it is not needed and allocating it into more crucial avenues, li
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    e child care and the creation of jobs. He even takes responsibility for the corruption of the actual president and gracefully "dies" as the actual president is dying so the vice-president, a man of gr
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    at integrity who was maligned by the power structure, could take over in his rightful place. The movie is, of course, a fantasy. Sadly, we would never elect a man of such integrity - a straightforward,
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    onest, caring, and financially middle-class man like Dave. Our election process does not allow for this.

    Revamping our election process would give people like Dave an opportunity to run for office. We
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    esperately need people who care more for the common good than for their own popularity. We need brilliant, creative, honest and caring people to lead our country, but this will never happen with our pre
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ent election system. We have incredible talent in this great country of ours, talent that could eliminate hunger and homelessness, and heal the internal wounds that create health problems, drug abuse,
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    racism, violence and crime. But this talent is rarely tapped because running our country has been based on the earthly values of greed and power over others rather than the spiritual values of honesty,
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    ompassion and caring.

    Unfortunately, neither our government nor most big businesses are based on the spiritual principles of compassion and caring about the common good. I have no doubt that if our gover
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ment was based on spiritual principles we would not have the hunger, homelessness, crime, health problems, and drug abuse that are endemic to our modern society.

    Article written by Margaret Paul, Ph.D


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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