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I sat here this morning, and decided to work out exactly how much time I use on creating my weekly ezine, and I almo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

st kinda shocked myself. I`m not the ONLY publisher who refuses to automate, so please, after reading my hours, spar

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

a kind thought for all those other publishers out there that do everything manually, and who really take the time t

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

get down to a personal level with their subscribers.

Typical daily hours for me as an ezine publisher

- Reading o

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

her ezines/newsletters: About 4 hours per day.
- Looking for the right content: 5-6 hours per day
- Checki

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

g email other than newsletters: 5 hours per day
- Getting rid of junkmail: 3 hours per day
- Staying in to

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

uch with other publishers, website owners etc.: 3 hours per day
- Working on learning html: 2-3 hours pr day

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

- Updating ezine, ads and slot-ads with Rich, my programmer: 6 hours per day (with about 10 hours "allsorts" chat

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

oo)
- Looking in forums for things of interest: 1-2 hours per day
- Reviewing articles for possible public

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

tion: 3-4 hours per day
- Chatting on msn and yahoo messengers, whilst looking for more ideas and helping peopl

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

: 12 hours per day
- Promoting ezine: At LEAST 4 hours per day (including submitting my own articles)

That

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

53 hours per day. Thank my lucky starts I`m great at mutli-tasking...hehehe

Remember, a lot of us do this to bring

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

you information that we hope will help you in some way or other, and I know how much it brightens up my day when I g

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t a mail saying "Great issue, Anna, Keep up the good work!" So I`m guessing a lot of other ezine owners would really

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

appreciate something like that.

Putting out an ezine is a LOT more than just slapping together a couple of articles

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

and a bunch of ads in an email, or on a website. I know there`s a lot of that going around too (I DO actually get to

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ns of those ones in my mailbax daily too), so if you`re subscribed to a great ezine, take the time to let the publis

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

er know, vote for them, recommend them to your friends, most importantly: Give Them Your Feedback!!

At the same tim

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

, if there`s something you DON`T like, let them know that too. Without subscriber feedback, we`re basically just pok

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ng around in the dark, hoping that we are giving people what they want. We are there for you, please be there for us

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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