Main Subject - Internet and Businesses Online

An ezine, also know as an email magazine, online publication or electronic newsletter is simply a newsletter available via email and/or online. There are hundreds of thousands of ezines on various subjects available on the Internet free of charge.

Having your own publication will not only enable you to keep in touch with your visitors, but it will help you build a huge database of targeted customers. If you'v

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e been marketing on the Internet, then you know it may take several contacts with a prospective customer before closing a sale. What better way to make those contacts, without spamming... In addition, you can eventually make a nice income selling sponsor advertising and classified ads.

You can publish an ezine completely free. Yahoo Groups http://groups.yahoo.com will host your list (ezine) free of charge. In

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

addition, they take care of all your subscription requests so you won't have to. To use one of these list servers, simply sign up and instantly create your list. They will provide you with a subscribe and unsubscribe email address and even a list owner email address, all completely free. The only disadvantage is that each posting will contain an ad for their service. This is really a small price to pay for suc

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

h a great service. If you're just starting out, utilizing one of these free services can simplify the process.

- CONTENT -

A quality ezine should contain at least some original content. Don't let the fear of writing intimidate you. If your ezine's focus is on an area of your expertise you shouldn't have any problems coming up with something to write about. If you've been out of school for a while, you might

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ant to freshen up on your writing and grammar skills. Visit any of the sites listed below for a crash course.

11 Rules of Writing -
http://www.junketstudies.com/rulesofw/

Exploring English -
http://www.shared-visions.com/explore/english/

Simpler Words And Phrases -
http://www.smartbiz.com/sbs/arts/tpl5.htm

Here are some additional resources for obtaining free content for your publication. Be

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ore using any articles, make sure you review the author's copyrights and make certain the article may be published. If you're not sure, contact the author and request permission to publish their article. Most articles for publication can be used in your ezine free of charge as long as the authors credits or resource box is included.

- FREE CONTENT -

Web-Source.net
http://www.web-source.net/free_articles

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

.htm

GoArticles.com
http://www.goarticles.com

1st-in-articles.com
http://www.1st-in-articles.com

EzineArticles.com
http://www.ezinearticles.com

- FOCUS -

Your ezine should focus on a subject in which you have a great deal of knowledge. If you have a web site, you should also take into consideration the focus of your web site; i.e., If your web site's focus is on Internet Marketing, you woul

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

n't want to have your ezines focus to be on "Animals & Pets," you would want it to be on "Internet Marketing."

- TITLE -

The title of your ezine is one of the most important decisions you can make. Many e-zine listing sites list their ezines in alphabetical order. By selecting a title such as, "Advertising Secrets" instead of "Working Online," your publication will be listed towards the top instead of the bo

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ttom. This will give your publication an advantage over the publications listed below yours. Potential subscribers will see your ezine first and be more apt to subscribe.

Your title should sound intriguing and tell your potential subscriber exactly what your publication is all about.

- PUBLISHING SCHEDULE -

You can publish your ezine as often as you like. When you first begin you may want to only publish on

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e a month until your subscriber base has grown. You can always increase your publication to bi-weekly or weekly whenever you'd like.

- SIZE -

There has been a great deal of controversy over the size of an ezine. In my humble opinion, size really doesn't matter. If you publish a quality e-zine with a great deal of content, I don't feel that your subscribers will care what size it is within reason. You should;

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

however, take into consideration that your subscribers may not want to download it. If it is too large, America Online will automatically turn it into a file attachment. Consider either condensing it or separating it into "Part One" and "Part Two."

- WEB SITE -

It isn't imperative that your ezine have its own web site, however, it is HIGHLY recommended. Having your own site will enable you to give your visit

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ors an in depths look at exactly what your publication is all about. You can include highlights of upcoming editions, polls, archives and a subscription box to allow your visitors to easily subscribe.

- ADVERTISING -

You should probably wait to begin selling advertising space until you have at least 1000 subscribers. You can sell ad space for $25 for every 1000 subscribers you have. There is a lot of adverti

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ing competition to take into consideration when selling ad space so, you may want to begin selling your ad space at a lower rate or offer special incentives; i.e., Buy two weeks of advertising for $20 get the third week free. Try to limit the number of ads per issue to ten and place them in the center of your publication. This will not only ensure adequate exposure for your advertisers, but your subscribers wo

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

n't be overwhelmed with advertising as well.

- STYLE & FORMAT -

The appearance of your ezine is one of the most important factors in determining your e-zine's success. Getting subscribers is the easy part. Keeping them will entail a little work. A professionally written, well designed, content rich publication will ensure your ezines success.

When formatting your ezine, keep in mind there are many different

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

types of email programs and they are not all created equal. As a general rule, to accommodate all of your subscribers and their different email programs, it is probably best to write your ezine in plain text. As with email programs, word processing programs are not all created equal as well. Your regular word processing programs are great for writing business letters, sales letters, etc., but not a good choice

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

for writing your newsletter due to formatting issues.

A good program to consider using is Notepad. This program should already be on your desktop.

Another consideration of great importance is your line length. If your text lines are too long, some email programs that aren't capable of viewing long text lines will force the last few words to the next line and your text will be viewed like this:

When formatti

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ng your publication your text length is one of the most important factors in determining how professional your publication will appear.

As a rule, a generally safe line-length is 65 characters (including spaces).

As you begin typing your text, when you reach 65 characters, use a hard carriage return. (Hit Enter)

If you'd rather not have to worry about hard carriage returns, you might want to use a progr

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

m called "TextPad". http://www.textpad.com/. This program can be set to automatically insert a hard carriage return when your text has reached 65 characters.

When you're ready to begin, make an outline for the contents of your e-zine to enable you to create a template.

After you've written your publication and you're ready to copy & paste it into your email program, make certain your email preferences are se

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

t to allow at least 65 characters of text per line. If your preferences are set for less, when you paste your text to be mailed it will appear to be improperly formatted.

It is highly recommended that you send a sample copy of your publication to yourself prior to sending it to your subscribers. By viewing your publication in this manner you will get an idea of what your subscribers will see and it will enabl

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

you to correct any formatting problems.

Publishing your own ezine is one of the best marketing decisions you'll ever make. Take your time, research your subject and design a publication of quality, useful content.

For further information on publishing your own ezine, you may download the free ebook entitled, "Ezines: A Complete Guide to Publishing." This free e-book received a 4-star Editors Pick from ZDNet

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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