Main Subject - Internet and Businesses Online

Have you ever transferred a domain name to another registrar and then noticed that you never received an extra year to your expiration da

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

te? Let me tell you what happened and what actions you can take!

The number one thing you need to realize in this situation is that the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

additional year is not controlled by the gaining registrar and it's not controlled by the losing registrar. It's controlled by the regist

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ry!

When a domain expires, the registry gives the losing registrar a grace periond in which they may renew the domain name. During this

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ime, your domain is most likely in a registrar-hold status and can't be transferred. So, you renew the domain name with your current regi

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

strar to get it in an active status again. This renewal extends the expiration date 1 year. So let's say you expiration date is now in 20

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

08. Then you initiate a transfer to another registrar. The transfer completes and the registry adds another year to your domain name. How

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ver, you look and see that it's still expiring in 2008! What happened?

Well, when your domain is renewed and transferred during the regi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

stry's grace period to the registrar, the registry actually REFUNDS the losing registrar the money for the renewal and takes the renewed

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

year off the domain name. (That's right folks, the losing registrar has received back the money they paid the registry for the renewal of

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

the domain name.)Then after the registry moves the domain name to the new registrar, it adds a year to the domain name. So your domain wa

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s renewed to 2008, then the renewal was refunded to the losing registrar and the year goes back to 2007, then the domain is transferred a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nd a year is added making it 2008 again.

Yet, you have paid for a renewal and paid for a transfer which adds a year! Can you get your mo

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ney back? Good question! I wish the answer was as easy as you think. There are many registrars who will refund you the renewal fee you pa

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

d, but not without a fight. You are almost always going to have to speak with a supervisor, and if possible, talk to the corporate team w

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ho handles the "big" complaints. In the end, the registrar might say that you were not paying for the addition of a year, but you paid fo

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

r the domain name to be set into an ACTIVE status again. It might be a lousy thing to do, but if they define a renewal as adding a year u

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

der X, Y, and Z circumstances, you don't have much of a fight. Your best bet is to get to a higher ranking person in the support center,

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

explain exactly what happened, how it happened, and explain that the registry actually refunded them for that renewal you paid for - all

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

while keeping calm, then you are more likely to get your money back. Just make sure you call the losing registrar and not the gaining one

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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It seems that the Internet is full of applications that allow tour operators, independent hotel and motel owners and packaged vacation providers with online booking capabilities. Here are some important things to keep in mind as you begin your research and compare the products.

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