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Main Subject - It Happened Again: GM to Lay Off Significant Numbers
It has happened again, and again in a very big way. I am sure you have heard the news that General Motors has announced they are closing plants and letting some 30,000 people go. Some they will be able to relocate, some they won’t.
Ford announced they are laying off over 4,000 people as well. This is all devastating news that we should all be concerned about.
The manufacturing
Ford announced they are laying off over 4,000 people as well. This is all devastating news that we should all be concerned about.
The manufacturing
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
sector of our economy is the one sector that provides for our society a “ladder” to allow us to move from lower class economies to middle and upper middle class economies. Without manufacturing, it becomes more and more difficult for families to pull themselves up and obtain the Great American Dream.
Most manufacturing jobs provide up to nine other jobs in the local economy. Thin
Most manufacturing jobs provide up to nine other jobs in the local economy. Thin
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
about the local drug stores, dry cleaners, car washes, gardeners, fast food restaurants, independent auto mechanics, and so on, that are going to see their customer base diminish and their services not used as frequently. This will be a direct result of their local patrons no longer have the discretionary income they once had. Most of those that are being laid off will now start
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
o learn how to get it done themselves. After all, they will now have the time. Many will begin working on their own cars, taking care of their own lawns, cooking and eating “in” more often than not.
And with fewer “end” products being produced, suppliers and their employees are affected in the same fashion.
What of our younger generation that is coming up through high school. W
And with fewer “end” products being produced, suppliers and their employees are affected in the same fashion.
What of our younger generation that is coming up through high school. W
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
at direction do they take upon graduation? What field do they now study in college? And to learn a trade is still a good bet, but unless they move to an area where there is more discretionary income, what do they learn a trade in?
These are tough situations and difficult questions. These actions affect us whether we live nearby or not, were laid off or still working. How much w
These are tough situations and difficult questions. These actions affect us whether we live nearby or not, were laid off or still working. How much w
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
ll the government be able to do to help us? I spoke with some friends who live in Marathon Florida who were devastated in the last hurricane and they related that FEMA has notified them that they are temporarily out of money due in large part to hurricane Katrina. They indicated that FEMA told them tehy need to go back to congress to get more moneys approved.
There were some indi
There were some indi
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
iduals who had some foresight and started a home based business that provided them residual income. It may have sounded kind of corny then, or out of vogue, but there are those families, husband and or wife: single parent, or head of household that DID do something way back when and have been enjoying discretionary income month after month from their home business.
To those who we
To those who we
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
e prepared, you will have a little less worry and frustration than those that did not.
For those that did not have a home based business and consequently no monthly residual income, it is never too late to start one. You can start one up for relatively little cost, and it will not dig into your new budgeted spending pattern if you start a business where the products would be those
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
that you consume in your household each month (all businesses need to have products or services sold. If not, then they are a scam and turn away as fast as you can).
As independent adults that are getting caught in this layoff trap and having less and less security, there are some analyses that may be difficult, nevertheless, need to now take place. For those of us not directly c
As independent adults that are getting caught in this layoff trap and having less and less security, there are some analyses that may be difficult, nevertheless, need to now take place. For those of us not directly c
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
ught (yet), this analysis process would still be good for us to examine as well.
First, hopefully those employees getting laid off have put back some savings. After all, this has happened before, so hopefully there was foresight that something like this could happen again and there was at least some preparation.
Second, take a real hard look at what areas you would be able to tri
First, hopefully those employees getting laid off have put back some savings. After all, this has happened before, so hopefully there was foresight that something like this could happen again and there was at least some preparation.
Second, take a real hard look at what areas you would be able to tri
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
, immediately if you have to, in order to slow down the cash outflows every month. Look at these areas closely. If you have teenage children, you might want to involve them in the process. Have them help to contribute ideas that will help the family weather this storm. Explain to them that as parents, you will do everything you can to make this a temporary situation and explain
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
to them you appreciate their help and input.
Third, “write down your plans”. This is so important. Set some short term goals that will help you to get through this time. Also make sure to include your “written” finances from step 2 here as well. One technique to use is to sit down and write out where the money is currently being spent now, and keep in mind that most of us don’t
Third, “write down your plans”. This is so important. Set some short term goals that will help you to get through this time. Also make sure to include your “written” finances from step 2 here as well. One technique to use is to sit down and write out where the money is currently being spent now, and keep in mind that most of us don’t
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
have the patience to do this, or are not honest enough with ourselves when we write it down. This is an important enough step that it is worth repeating. Look at the list and decide what, if any, areas you can trim down for the interim period. Don’t look at it as “I can go without this” because this will begin to breed anger, after all, you worked hard for X amount of years and
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
ou deserve this (whatever “this” is). And anger will do you, and or your family and friends no good at all. This is not the end of the world and you and your family will survive it. YOU MUST REMEMBER THAT! But if you have the wrong mindset, it will make the process you are getting ready to go through much more difficult than it needs to be.
Once you have it all written down, ta
Once you have it all written down, ta
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
k to your spouse, or if a single parent, talk to your children and try and solicit their support in “making those new plans happen”. If the family has goals, and “everyone” in the family participates, this temporary setback will be brief and the family will remain intact. If there are no goals, or they are not specific, then everyone does what they think they should do and in real
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
ty, nothing gets accomplished except feelings of contempt and frustration for one another.
Keep in mind that this has happened to people and families in the past and it will be experienced by people and families in the future. You may find that your life begins moving in a direction you had not originally intended it to, or the changes that take place in you or your family are cha
Keep in mind that this has happened to people and families in the past and it will be experienced by people and families in the future. You may find that your life begins moving in a direction you had not originally intended it to, or the changes that take place in you or your family are cha
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
ges you would not have thought possible before. That will be ok. Again, the most important thing to remember is that you did just fine up to this point and you will do just fine after this. There is a life after (insert you company name here). Sometimes many believe that a power greater than they are found it necessary to challenge them to learn and experience new situations tha
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
will further develop their true selves, or the people they were intended to be. Some will shrug their shoulders and say ok, let’s move on.
Situations have a way of correcting themselves in time, but usually not without some direct input from us. What this means is if we are to have a positive outcome, we need to have positive input. If we experience a negative outcome, then we o
Situations have a way of correcting themselves in time, but usually not without some direct input from us. What this means is if we are to have a positive outcome, we need to have positive input. If we experience a negative outcome, then we o
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
viously have input negative actions, feelings and or emotions.
Remember, this is not the worst thing that could have happened. If you were not ready for this one, then get ready for the next one. Seriously examine your spending patterns. Take a hard look at where your money is going. Employ a technique called delayed gratification, meaning wait and save the money for the item,
Remember, this is not the worst thing that could have happened. If you were not ready for this one, then get ready for the next one. Seriously examine your spending patterns. Take a hard look at where your money is going. Employ a technique called delayed gratification, meaning wait and save the money for the item,
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
r do what is necessary now, in order to have the item or pleasure in the future.
And if you do not have a side business, a home based business, or a part time business, realistically pursue that. There are too many opportunities that are out there for bright people that are hard working in nature, to sit on the sidelines and not be able to participate in the “Great American Dream”
And if you do not have a side business, a home based business, or a part time business, realistically pursue that. There are too many opportunities that are out there for bright people that are hard working in nature, to sit on the sidelines and not be able to participate in the “Great American Dream”
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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