Main Subject - Business

Why is it that some people are always noticed, and others seem to vanish away into the woodwork? Why do some individuals become “people

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

magnets,” who can persuade others with a few choice words? The answers to these questions are of importance to anyone hoping to advanc

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

in life and to have satisfying relationships. They are Presence and Charisma.

I have met many people who have this “presence” or “aur

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

.” In the Eastern world it is often thought of as another manifestation of “Qi.” Closely related to “presence” is charisma: a compellin

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

attractiveness or charm that can inspire devotion in others. In the ancient world charisma was thought to be a divine power or talent,

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

and the word comes from the Greek word kharis meaning “grace” or “favor.” There is a small scientific literature on this phenomenon of

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

harisma, which often flows from having a strong presence. There are clearly many types of charisma: Political, sports, performance, bus

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ness, spiritual, literary. scientific and so on. The only two people whom I’ve met who knew Einstein told me that people would usually

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ll stand up when he entered the room. Charisma is more than just a personal characteristic; it can also be conceptualized as the way in

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

which certain groups interact with each other.

Clearly some people have presence and charisma. The question is whether they can also b

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

developed. The answer is yes, they most certainly can be. Presence is created by an overall impression constituted of posture, eye con

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

act, stillness, silence, self-confidence, competence and serenity. People with a strong presence are often a little mysterious, in the

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ense that they tend not to reveal much about themselves or their accomplishments. I have also felt if very strongly in people who have

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

orked to develop the subtle systems of their bodies. One of the most potent examples was a Korean Ki-Master who spoke not a word of Eng

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ish, but whose presence could be felt the moment he entered a packed room. Work on your subtle systems will likely cause you to be more

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

still and serene and to have a better posture.

There are a number of things that you can do to improve your own charisma:

1. Create a

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

strong first impression by developing your presence
2. Develop a good impression when you speak
3. Be a good active empathic

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

istener who connects with other people and asks pertinent questions
4. Be supportive of other people and their aspirations
5.

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

Be persuasive
6. Be resilient and adaptable
7. Expand your vision of what is possible
8. Practice thinking creatively

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

9. Use humor
10. Be committed and courageous
11. Initiate persistent action
12. Instill hope in the people around yo

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Newsletters remain a powerful marketing tool because they are targeted, specific, and often eagerly welcomed communications from you directly to your customers. Your newsletter mailing list can be pure gold, and the quality of your newsletter can help retain customers. However, few companies produce newsletters nowadays. They seem old-fashioned. However, newsletters still work today.

Thoughtfully defining your business – and your differentiation - will help you to understand who you are, what you do, and what makes you different. Not many small businesses take the time to answer those core questions about their business, but those answers are essential to creating a strong brand identity, focused messaging, and effective marketing materials. Having these will make a stronger impression on your target audience – once you stand out, they’ll be more likely to remember you when they have a need for your products or services.

Does good customer service extend to all customers? Read on - and put on your thinking cap!

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