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    Did I get your attention? Or do you see so many advertisements with people giving free things away that you just don't even pay attention anymore? When
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    is something worth paying for? Do you value something less when you got it for free? Does the value of something go up proportionately in your mind to
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    the cost you paid for it? And then again, how often have you paid for something, only to realize that it's value is far less than it was advertised to be
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.



    What brought this to my mind this week relates very directly to an opportunity in which I recently became involved. This is a fun one, and I am doing
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    uite well in it. One of my downline members, "Pete" is a very active marketer and he has set up a forum specifically relating to this project. I have b
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    en approached about the use of a splash page I created by "Bob" one of Pete's downline signups.

    Now the way this particular program is structured, I wou
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    d not receive any monetary value from Bob's work, even if he signs up 1000 people. But, I am willing to do the work for Bob and create a splashpage just
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    for him and help him with his marketing. I have no intention of charging Bob for this.

    But it got me thinking... if we are working out here in this ju
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    gle of internet marketing, our perceived goal is to make money. Most of us aren't doing this with any charitable overtones! Certainly, our time is of va
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ue. So, my original question -- when does it make sense to charge for your time, and when does FREE make sense?

    My answer to this question may not be t
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    e same as yours. But if I can see a long term benefit to myself, then I am willing to forego the immediate possible monetary compensation. In the above
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    instance, here is why I choose the FREE option:

    • I will have made a friend of Bob, and probably of Pete also since I am caring for his downline
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
  • Since the splash page I am making is being given to Bob, he will not object if I place an advertisement at the bottom of it asking people to si
  • cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    n up for my ezine, which will potentially bring me new subscribers.
  • Bob is willing to sign up underneath me in my autoresponder to handle all of
  • tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    he leads he will be getting from this splash page, so I will make a small commission there.
  • Both Bob and Pete will be "warm" contacts and more in
  • t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    erested in looking at opportunities I may offer them in the future. So should you always give your work away in the hope of future monetary rew
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    rd? Certainly not! But the real key to this is value! Even though in the above instance I am not getting a "check in the mail" for creation of the spl
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    sh page, the value I will receive will be worth my time and effort. This is the essence of the "social networking" we all hear so much about.

    Next time
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    you are approached with an idea, a proposal to get involved, or a FREE item, take a second and think of value. What will the value be to you? Don't be
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    fraid to say NO! Just remember though - value is not always measured in dollars and cents. Often the intangibles are of far greater value than monetary


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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