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  • Main Subject - Your Direct Mail Donors Should Be Arrested (By Your Letter Opening)

    The first time I was shelled by enemy artillery, I learned a vital lesson that applies to the success of your fundraising letters.
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    r>
    I was lying in a slit trench on Mount Wall, about 35 kilometres west of the town of Stanley, in the Falkland Islands. The year
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    was 1982, the Falklands War. The Argentines were lobbing 105mm Pack Howitzer shells around my position, trying to dislodge my Royal Ma
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    rines Commando troop.

    But their fire was ineffective.

    You see, the soil in the Falkland Islands consists largel
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    of peat bogs. The soil is dense and wet and soft underfoot. That means the enemy’s artillery rounds penetrated the soil before detona
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ing, sending most of their force and shrapnel upwards rather than horizontally, in my direction.

    When you want to leave a
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    lasting impression on your target audience, you must use the right ammunition. If the Argentines had used the kind of artillery shells
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    that explode above the ground rather than in it, you would not be reading this article today.

    So here is the principle appl
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    ied in practice, in the battle for the mind of your target audience. You must open your fundraising letters in such a way that you com
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    el your donors to read on right to the end, and take action. Your opening sentence is the most vital sentence in your letter. If you u
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    e the wrong ammunition here, your letter will misfire.

    So start your letters with your largest cannon. Grab your prospect’s
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    attention so that he simply has to read on.

    Here are some creative examples of ways to do that.

    Pose a provo
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ative question
    “What happens when a snow leopard catches a cold, a walrus has a toothache or a 3,000-pound rhino comes down w
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    ith an intestinal disorder?”

    Start with an arresting story
    “She stood on the curb looking scared and lonely in
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    skimpy halter top and bright red lipstick. It was two in the morning. A chilly breeze whipped up in the street and seemed to make her
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    shiver. She was a child . . . just a child. We pulled our Covenant House van up to the curb and rolled down the window . . . .”
    <
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    br> Open with a scintillating (and relevant) quote
    “’I complained because I had no shoes, until I met a man who had no fe
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    t.’ Perhaps your parents taught you this when you were young. Mine did. It keeps things in perspective, and I have learned, in my bett
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    er moments, not to complain.”

    Present an arresting fact
    “America’s neglect is killing our children. In the past
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    year, 40,000 babies like Andrew died before their first birthday. Virtually no other industrial nation lets so many of its babies die.


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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