Main Subject - Business

IBM, which registered 3248 patents last year, has decided that sharing technology can sometimes be more profitable than jealously guarding its pr

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

operty rights on patents, copyrights and trade secrets (Herald Tribune, April 11 2005).

International Business Machines have come to the above c

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

onclusion 205 years after the invention of electric light – thus clearly illustrating that even the 19th largest company in the world (fortune.co

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

m) with a market capitalization on $141 billion (nasdaq.com) is still only learning about creativity and innovation.

Of course the issue of cont

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ol is important but a quick history lesson indicates that the above should not have taken so long!

The first electric light was made in England

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

by Davy, in 1860 Swan attempted to devise a long lasting light using carbon paper, in 1877 Brush lit up Cleveland Ohio and in 1879 Edison began w

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ork on a practical light bulb that would eventually glow for 1500 hours.

Recently, Linux – open source software developed through collaboration

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

n the Internet – has grown to the extent that it is closing in on Microsoft’s market share (news.com).

The above two examples indicate a number

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

of factors about creativity and innovation that IBM should have learned a long time ago, some of which include:

a) Creativity (problem identific

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ation and idea generation) and innovation (idea selection, development and commercialisation) can take years and use huge resources – collaborati

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

n, networks and shared tacit knowledge rapidly reduce investment and rapidly increase speed to commercialisation.

b) Radical changes result from

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

incremental improvement.

c) Radical shifts require the input of new knowledge.

d) New knowledge and incremental improvements result from elici

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ting tacit knowledge from a broad knowledge base.

e) New knowledge and incremental improvements result from eliciting ideas from a number of sou

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

rces, a number of diverse sources and a number of novel sources – by utilising networks.

f) New knowledge and incremental improvements result fr

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

m eliciting ideas from a number of sources, a number of diverse sources and a number of novel sources – through collaboration.

In conclusion, th

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

e probability of producing world changing innovation in-house is low. The knowledge pool is simply too shallow. And that can be said without cons

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

idering motivation, group structures etc etc etc.

This topic is covered in depth in the MBA dissertation on Managing Creativity & Innovation, wh

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ch can be purchased (along with a Creativity and Innovation DIY Audit, Good Idea Generator Software and Power Point Presentation) from http://www

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

.managing-creativity.com. You can also receive a regular, free newsletter by entering your email address at this site.

Kal Bishop, MBA

********

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

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tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Main Subject - Innovation Management - IBM Opens Lid On Its Treasure Chest

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