Main Subject - Business

If you have company delivery vehicles at your small or medium sized business you should have

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

a preventative maintenance schedule and procedures for employees who are drivers of these veh

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

icles. When discussing preventative maintenance over the years with business owners the first

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

thing which comes to mind is ‘Oil change’ and usually the business owner who is on the hook

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

or the loans on these vehicles is more than aware of that fact. Yes, you should change the oi

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

l. Obviously you should. How about every 3,000 –5000 miles. After all, that kind of drivin

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

g is hard on a vehicle, not to mention:

Starting and stopping

Speed bumps

Stop and go traf

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ic

Water movement

Workers driving truck

Driving in dusty conditions

Towing trailers

Exce

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ssive idling

While you are waiting to fill up with gas, you should have employees Armor-All

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

the tires, hand out business cards, wipe off rims, clean inside windows and:

Check engine o

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

l level, add as required

Check windshield washer solvent and add if required

Once per month

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

you should do an extensive pre-flight check of your truck. On the first Monday of each mont

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

h:

Check tire pressure and look for unusual wear or damage

Inspect battery and clean and ti

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ghten terminals as required

Check fluid levels of coolant reservoir, power steering and tran

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

mission and add as needed

Check all lights and all other electrical items for correct operat

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ion to prevent fix-it type tickets humiliating your driver and detracting from your company s

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ince the logos are on the side of the vehicle for advertising. Develop a quick form with the

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e items listed and be diligent about checking them on a certain day each month, you will be g

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

lad you did, it adds money to the wholesale value of the vehicle and could save your small bu

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

siness thousands of dollars in unnecessary repairs, towing and lost business due to down time

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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