Main Subject - Business

You must determine quickly which of your new subordinates will be valuable to you and which will work towards their own goals. Set them t

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

o work immediately on various tasks that will help you but are not vital to your success. Make them earn their stripes. Perform constant

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

pot checks on their progress to see who is working. Many will assume that once employed they have no need to work anymore and can now goo

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

off. Disabuse them of this notion immediately and give them the worst of the work that needs doing. Inform them that if they finish this

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

filthy work they will be given better jobs in the future.

Never trust the subordinates that want power for power's sake. These will use

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

the power you give them to attack you. Watch them closely and follow the old Mafia maxim of "keep your friends close but your enemies clo

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

er." Slander them to your closest lieutenants and encourage them to spread these slanders; all the better if they are true. However, in t

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

his case, do not allow the truth to be a barrier to tearing down these enemies. If you genuinely have a clear vision for the future and y

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

u truly believe that your vision is the best then use all the weapons in your arsenal to achieve victory. Rumors can be more devastating

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

han daggers.

Remember that rumors cut both ways. As former prime Minister Margaret Thatcher stated "I don't mind how much my Ministers t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

lk, so long as they do what I say." Chances are those closest to you will be the most likely to wag their tongues. Let them as long as th

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ey obey you in the end. People in positions of authority talk to make themselves seem important to others. What better means of making yo

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rself seem mighty then to slander the boss? Allow it within reason. Crushing the slanderer will only cause more rumors.

And if they shou

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

d pass your initial tests start giving them more advanced and complex tasks which will serve to test the limits of their abilities. Some

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

will always rise to the occassion and perform at the expected level. These will be your greatest resources and also your greatest threats

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Ensure their loyalty for all time by tying their goals and aspirations to yours. Show them the commonality of your dreams and work to ma

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e them one. Prove to this "rising star" that you are the best chance to achieve their ultimate goals.

If you cannot prove your superiori

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ty then you must decide who will be the better leader. Do they refuse your leadership because of obstinance or are they truly better suit

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

d for the task? Make your decision and then act upon it in a course of action suitable for your ends. Beware of attacking this rising sta

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

directly as it might lead to your rapid decline from power. Far better to agree to a limited sharing of power than to lose it completely

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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