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    I've long been a believer that businesses owners must maintain an awareness of their standing in two highly competitive and equally important arenas.

    1. Com
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    petition for customers

    2. Competition for the talent needed to attract, serve and maintain those customers.

    Some attrition is natural in both arenas. Signi
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    icant defection in either area will adversely affect the other. Because this is a briefing, let's examine one element of defection: employees who voluntarily
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    leave and why.

    The July 2006 issue of Workplace Solutions Magazine published a list of the top reasons people leave their jobs. (Note: these are listed in n
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    particular order)

    The Top Five Drivers of Voluntary Terminations

    * Relationship with Manager

    * Opportunities for Growth

    * Workload

    * Organization

    * Co
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    pensation

    What Are You Hearing?

    Of these five reasons, which one do you hear most frequently? I am willing to wager that it is the last one on the list, "M
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    re money." Why? The authors of the book Play To Your Strengths provide some insight about a potential flaw in the exit interviewing process they call the Say
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    Do Trap. Just as political pollsters face challenges with the accuracy of their responses, the same is true for exit interviewers. What employees say is not
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    lways what drives their behavior. Exiting employees who prefer not to burn bridges may be saying that they have found a position for more money. But that ans
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    er often masks the real issue. Compensation is a socially acceptable reason to leave and it typically will not be challenged. The exiting employee can easily
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    avoid having a potentially uncomfortable conversation about the real reasons that led them to seek a happier workplace. While their search may have coinciden
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    ally resulted in higher pay, the reality may be that they would have been content to work for less money just to escape a bad situation.

    There's Something E
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    se About Mary

    Here's a hypothetical scenario about "Mary". Mary tells her exit interviewer that she got "more money" elsewhere while her real reason for dep
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    rture is that her manager is a condescending, incompetent idiot. Mary is one of several in her department who have recently left for that same stated reason,
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    more money. To address this defection problem uncovered by socially correct exit interview responses, what does management do? They decide it's time to rai
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    e the department pay scale. So, not only has the exit interview failed to get to the root cause of the problem, misinformed management's remedy results in an
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    unnecessary increase in overhead. They succeed in slowing down turnover by creating a barrier to exiting in the form of combat pay that is not easily exceede
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    . But what happens to productivity in this manager's combat zone of a department? The company now pays more for less output.

    Take it to the bank…

    Whether
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    our dealing with the departure of either your external or internal customers, it's about more than money. There's always something else. In either case, it's
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    about the overall value proposition of your offering. In either case, examine your information gathering process to determine if your boat has sprung a leak


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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