Main Subject - Business

Sustained and long periods of sitting still at our desks are not good for our backs - this is obvious: but how best to reduce the risks of backache and related stress

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

? Getting up to stretch and walk around at regular interval makes very good sense, but many of us simply do not do it. And according to the British Chiropractic Assoc

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ation amongst others, this is one of many reasons why office-related musculoskeletal problems are still on the increase.

A feature of modern working life is how easy

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

it is to become trapped into a sedentary existence. We spend long periods using keyboards, even during lunch hour checking emails, and then in the car or on the bus o

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

train home. It should be no surprise that the result of so much time spent in a fixed position is an increase in the incidence of neck, shoulder and back injuries. A

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

d it really is no surprise that experts agree that it is vital to incorporate more movement and flexibility into what otherwise are quite static and sedentary working

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

roles. But how to achieve this?

A recent study reported in the industry press suggested that - as opposed to the age-old advice to sit up straight - a slumped posit

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

on actually appears to be the healthier option. The study at Woodend Hospital, Aberdeen, Scotland asked 22 volunteers with no history of back trouble to adopt a slouc

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

, a 90 degree and a 135 degree angled sitting position, whilst being scanned by an MRI scanner. The results showed the latter angled position to place least strain on

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

the lower back.

In spite of these somewhat controversial findings, office furniture commentators have agreed that up to a point, a reclining positio

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

can be beneficial, as long as the spine is properly supported through good a quality office chair, suitably adjusted. In particular, setting up the office chair with

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

a slight backward lean has always been thought of as an ideal posture - as long as the lower back is in complete contact with the back of the chair. However, such a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

osition is hardly appropriate for those involved in a great deal of typing and keyboard-related work, where leaning forward becomes the natural tendency.

One solutio

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

here is posture-monitoring software such as the proprietary PostureMinder which offers a neat software-based solution to the problem of injuries due to poor posture

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

t the desk. Such systems continually check your posture via a webcam, and deliver on-screen reminders to you when you have been consistently sitting badly for a minut

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

or two, for example.

Coupled with good quality office furniture and advice from ergonomic experts in its proper use, such solutions point a way for

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ward to the problem. Good office seating should follow the movement of the body and be flexible with it whilst supporting it. Chairs should always have a good, ergono

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ic, synchronised mechanism and come with solid practical advice.

However, in the end, with proper office furniture in place, plus footrests, flexible PC monitor adju

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ting arms, TCO approved VDUs and all other ergonomic hardware, it remains imperative to think less about the positioning of the equipment - important as it is - and t

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ink more about varying the position of the individuals using them, including constant reminders to take short breaks and varying the office routine as far as possible

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Are you frustrated with your office space? Do you hunt for a pen every time you put one down? Is the search for documents a half-day event? Is your paper filed chronologically - working your way down the pile to 'one week ago' and unable to pull out 'four months ago' for fear of a paper flood catastrophe?

The internet became one of the famous communication medium that aided to make things lighter and easier. Through the internet companies were able to extend their services online and had created website that will be easily accessed by their customers and clients.

This article discusses the importance of developing your people skills, perhaps just as important if not more, than your job-specific hard skills.

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