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    If you want to stay healthy as a business, it is necessary to provide some basic tr
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    aining to your customers on how they should do business with you.

    Let's look at an
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    example of how we train our customers to create problems for us. Suppose you have
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    policy of invoicing your customers on the first of the month and your terms are "D
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    e Upon Receipt."

    Very rarely does a customer drop everything and write a check tha
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    moment. A bill that is due upon receipt is already late, so a few more days won't
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    make a big difference. When the customer gets around to writing the check a few we
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    ks later, you deposit it and nothing is said. So your customer understands that yo
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    really did not mean "Due Upon Receipt", but rather "Due When You Get Around To It.
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    Businesses that allow a "When You Get Around To It" policy, will eventually creat
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    significant receivable and collection problems for their company, not a good thing
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a


    So how do you train your customers to pay on time? Look at your water or electri
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    bill. They all say "Due upon Receipt." But there is also another date on the inv
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    ice which says "Past due if not paid by..." And what do we do? We wait until the
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ill is just about to go past due, then we pay it. Why? Because we don't want to b
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    late, right? Even though we have established terms of "Due Upon Receipt", we must
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    still set a solid expectation with our customer as to when the bill is past due. Th
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    s also gives us a clear point where we can impose penalties for late payment.

    We a
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    e always training our customers in some way. Examine your policies and be sure you
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    are training them in a way that keeps you healthy and them happy!

    To Your Success


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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